VIRMA

Across TCGA patient cohorts, VIRMA protein abundance is significantly associated with the RNA expression of many other genes, with 16,782 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VIRMA-associated genes across cancer lineages are ANTXR2, LYVE1, and FLI1. Each is linked with VIRMA in more than 6 cancer types. Because this analysis shows association rather than direction, both VIRMA-to-partner and partner-to-VIRMA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VIRMA versus ANTXR2 in LSCC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIRMA→partner) and Y-score (partner→VIRMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANTXR2 →	-0.702	-0.227	<.001	<.001	3	7
BRCA	LYVE1 →	-1.532	-0.235	<.001	<.001	3	6
BRCA	FLI1 →	-0.791	-0.233	<.001	<.001	3	6
LSCC	DBF4B →	+0.720	+0.242	<.001	<.001	3	6
GBM	HPGDS →	-0.901	-0.274	<.001	<.001	3	6
GBM	ABLIM3 →	-1.104	-0.286	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,782 associations by consensus.

VIRMA vs ANTXR2 — LSCC

Explore this scatter interactively →