VIRMA

Across TCGA cell cohorts, VIRMA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,462 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VIRMA-associated GO terms across cancer lineages are Blastocyst growth, Protein localization to condensed chromosome, and Negative regulation of protein localization to centrosome. Each is linked with VIRMA in more than 14 cancer types. Because this analysis shows association rather than direction, both VIRMA-to-partner and partner-to-VIRMA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blastocyst growth grouped by VIRMA-low versus VIRMA-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VIRMA→partner) and Y-score (partner→VIRMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Blastocyst growth →	+0.205	+0.830	.001	<.001	3	15
BLOOD_Lymphoma	Protein localization to condensed chromosome →	+0.127	+0.621	<.001	<.001	3	8
BONE	Negative regulation of protein localization to centrosome →	+0.117	+0.761	.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of maintenance of sister chromatid cohesion →	+0.067	+0.584	<.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.067	+0.584	<.001	<.001	3	8
STOMACH	Cellular response to misfolded protein →	+0.135	+0.895	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,462 associations by consensus.

Blastocyst growth by VIRMA expression — STOMACH

Explore this box plot interactively →