VIM

Across TCGA patient cohorts, VIM RNA expression is significantly associated with the protein abundance of many other proteins, with 24,811 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VIM-associated proteins across cancer lineages are VIM_S214, VIM_S56, and VIM_S72. Each is linked with VIM in more than 9 cancer types. Because this analysis shows association rather than direction, both VIM-to-partner and partner-to-VIM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VIM versus VIM_S214 in BRCA, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VIM→partner) and Y-score (partner→VIM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VIM_S214 →	+0.861	+1.111	<.001	<.001	3	10
PDAC	VIM_S56 →	+0.975	+0.494	<.001	<.001	3	10
OV	VIM_S72 →	+1.738	+0.862	<.001	<.001	3	10
BRCA	VIM_S22 →	+0.956	+1.152	<.001	<.001	3	9
OV	VIM_S47 →	+0.861	+0.995	<.001	<.001	3	9
COAD	LGALS1 →	+0.814	+0.991	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,811 associations by consensus.

VIM vs VIM_S214 — BRCA

Explore this scatter interactively →