VIM-AS1

Across TCGA pan-cancer cohorts, VIM-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated VIM-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher VIM-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated VIM-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, SKCM, and UVM are the cancer types where VIM-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.761	0.611	<.001	107	view →
SKCM	OS	Tertile	All	0.422	0.227	<.001	69	view →
UVM	DFS	Median	III,IV	0.264	0.715	.003	66	view →
ACC	DFS	Tertile	All	0.444	0.814	<.001	60	view →
LGG	DFS	Median	All	0.618	0.860	<.001	54	view →
ESCA	DFS	Quartile	III,IV	0.585	0.181	.002	35	view →
KIRP	DFS	Tertile	IV	0.040	0.765	.010	25	view →
UCEC	OS	Quartile	All	0.861	0.700	.005	24	view →
LIHC	DFS	Tertile	III,IV	0.564	0.153	<.001	20	view →
BLCA	OS	Quartile	All	0.349	0.511	.010	19	view →
PCPG	DFS	Tertile	All	0.982	0.817	.006	19	view →
LUSC	OS	Median	III,IV	0.457	0.938	.007	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

VIM-AS1–LUAD (OS)

Open the LUAD breakdown →