VIL1

Across TCGA cell cohorts, VIL1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VIL1-associated genes across cancer lineages are C10orf53, PRAMEF9, and FAM24A. Each is linked with VIL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VIL1-to-partner and partner-to-VIL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by VIL1-low versus VIL1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIL1→partner) and Y-score (partner→VIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C10orf53 →	+0.023	+4.906	<.001	.006	3	1
URINARY_TRACT	PRAMEF9 →	+0.013	+5.087	<.001	.004	3	1
BLOOD_Leukemia	FAM24A →	+0.028	+4.384	.003	.006	3	1
BLOOD_Leukemia	GSG1L2 →	+0.034	+4.384	<.001	.006	3	1
BLOOD_Leukemia	MAGEL2 →	+0.297	+4.133	.008	.003	3	1
LARGE_INTESTINE	TBC1D21 →	+0.010	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C10orf53 by VIL1 expression — OESOPHAGUS

Explore this box plot interactively →