VGLL4

Across TCGA patient cohorts, VGLL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,049 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VGLL4-associated proteins across cancer lineages are VGLL4_S268, VCL_S346, and VCL_S795. Each is linked with VGLL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both VGLL4-to-partner and partner-to-VGLL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VGLL4 versus VGLL4_S268 in BRCA, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL4→partner) and Y-score (partner→VGLL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VGLL4_S268 →	+0.653	+0.579	.006	<.001	3	6
PDAC	VCL_S346 →	+0.579	+0.556	<.001	<.001	3	6
BRCA	VCL_S795 →	+0.441	+0.464	.001	.002	3	6
LSCC	PTK7 →	+0.509	+0.620	<.001	<.001	3	6
BRCA	SPARC →	+0.508	+0.614	.001	.001	3	6
BRCA	SRP68 →	-0.178	-0.478	.005	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,049 associations by consensus.

VGLL4 vs VGLL4_S268 — BRCA

Explore this scatter interactively →