VGLL4

Across TCGA patient cohorts, VGLL4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,571 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VGLL4-associated genes across cancer lineages are MKRN2, PTK7, and RBSN. Each is linked with VGLL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both VGLL4-to-partner and partner-to-VGLL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VGLL4 versus MKRN2 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL4→partner) and Y-score (partner→VGLL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MKRN2 →	+0.365	+0.337	.001	<.001	3	6
BRCA	PTK7 →	+1.090	+0.436	<.001	<.001	3	6
UCEC	RBSN →	+0.410	+0.326	.001	<.001	3	6
BRCA	ZNF462 →	+0.626	+0.178	<.001	.009	3	6
OV	SUMF1 →	+0.566	+0.239	.002	.007	3	5
LSCC	UBP1 →	+0.412	+0.421	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,571 associations by consensus.

VGLL4 vs MKRN2 — OV

Explore this scatter interactively →