Across TCGA patient cohorts, VGLL3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,174 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VGLL3-associated genes across cancer lineages are AHSG, GLUD1, and SUPV3L1. Each is linked with VGLL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both VGLL3-to-partner and partner-to-VGLL3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL3→partner) and Y-score (partner→VGLL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AHSG →	-0.512	-0.782	.007	.001	3	2
PDAC	GLUD1 →	-0.718	-1.041	.005	.004	3	2
LSCC	SUPV3L1 →	-0.719	-0.805	.001	.001	3	2
LSCC	TMEM246-AS1 →	-0.780	-1.063	.004	.003	3	2
LUAD	LINC00858 →	-2.565	-1.130	<.001	<.001	3	2
LSCC	TMEM44-AS1 →	-1.066	-0.778	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,174 associations by consensus.

Exploration

VGLL3 survival (RNA) · tumor vs normal (RNA) · all VGLL3 data types