VGLL2

Across TCGA patient cohorts, VGLL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,596 significant associations in total. STAD shows the largest number of these associations.

The most reproducible VGLL2-associated GO terms across cancer lineages are Mesenchyme morphogenesis, Muscle cell development, and Heart valve morphogenesis. Each is linked with VGLL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both VGLL2-to-partner and partner-to-VGLL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesenchyme morphogenesis grouped by VGLL2-low versus VGLL2-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL2→partner) and Y-score (partner→VGLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Mesenchyme morphogenesis →	+0.091	+0.387	<.001	<.001	3	12
UCS	Muscle cell development →	+0.061	+2.409	<.001	<.001	3	12
TGCT	Heart valve morphogenesis →	+0.079	+0.443	<.001	<.001	3	11
TGCT	Endocardial cushion development →	+0.097	+0.599	<.001	<.001	3	11
TGCT	Aorta morphogenesis →	+0.087	+0.411	<.001	<.001	3	11
UCS	Response to X-ray →	+0.049	+2.647	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,596 associations by consensus.

Mesenchyme morphogenesis by VGLL2 expression — TGCT

Explore this box plot interactively →