VGLL2

Across TCGA patient cohorts, VGLL2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VGLL2-associated genes across cancer lineages are CLP, MEP, and Th2 cells. Each is linked with VGLL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VGLL2-to-partner and partner-to-VGLL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by VGLL2-low versus VGLL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL2→partner) and Y-score (partner→VGLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLP →	-0.074	-3.169	.014	.019	3	1
UCEC	MEP →	+0.043	+2.202	.001	.034	3	1
UCEC	Th2 cells →	+0.266	+3.177	.002	.010	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CLP by VGLL2 expression — UCEC

Explore this box plot interactively →