VGLL2

Across TCGA cell cohorts, VGLL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,844 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible VGLL2-associated GO terms across cancer lineages are Neuroligin clustering involved in postsynaptic membrane assembly, Spermatid differentiation, and Axoneme assembly. Each is linked with VGLL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both VGLL2-to-partner and partner-to-VGLL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuroligin clustering involved in postsynaptic membrane assembly grouped by VGLL2-low versus VGLL2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL2→partner) and Y-score (partner→VGLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Neuroligin clustering involved in postsynaptic membrane assembly →	+1.530	+0.122	<.001	.002	3	5
SOFT_TISSUE	Spermatid differentiation →	-0.030	-2.063	<.001	<.001	3	5
SOFT_TISSUE	Axoneme assembly →	-0.054	-2.281	<.001	<.001	3	5
BREAST	Lactate metabolic process →	+0.201	+0.084	<.001	.001	3	4
BREAST	Cytosolic ciliogenesis →	+0.152	+0.082	<.001	<.001	3	4
BREAST	rRNA processing →	+0.078	+0.077	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,844 associations by consensus.

Neuroligin clustering involved in postsynaptic membrane assembly by VGLL2 expression — BREAST

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