VGLL2

Across TCGA cell cohorts, VGLL2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible VGLL2-associated genes across cancer lineages are CST11 and OR11H6. Each is linked with VGLL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VGLL2-to-partner and partner-to-VGLL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST11 grouped by VGLL2-low versus VGLL2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL2→partner) and Y-score (partner→VGLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CST11 →	+0.065	+4.981	.006	.008	3	1
CNS	OR11H6 →	+0.035	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CST11 by VGLL2 expression — CNS

Explore this box plot interactively →