VEZF1

Across TCGA cell cohorts, VEZF1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VEZF1-associated genes across cancer lineages are KRTAP5-4, OPRM1, and PCARE. Each is linked with VEZF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VEZF1-to-partner and partner-to-VEZF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP5-4 grouped by VEZF1-low versus VEZF1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEZF1→partner) and Y-score (partner→VEZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KRTAP5-4 →	+0.101	+4.977	<.001	.007	3	1
BLOOD_Leukemia	OPRM1 →	+0.025	+5.201	<.001	.006	3	1
BLOOD_Leukemia	PCARE →	+0.028	+5.201	<.001	.006	3	1
BLOOD_Leukemia	SSX7 →	+0.044	+5.539	<.001	.003	3	1
BLOOD_Leukemia	OR10A6 →	+0.051	+5.201	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.329	+4.688	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

KRTAP5-4 by VEZF1 expression — SKIN

Explore this box plot interactively →