Across TCGA patient cohorts, VEPH1 mutation is significantly associated with the RNA expression of many other genes, with 5,960 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VEPH1-associated genes across cancer lineages are LINC01399, MED15P9, and B3GNT10. Each is linked with VEPH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both VEPH1-to-partner and partner-to-VEPH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEPH1→partner) and Y-score (partner→VEPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01399 →	+0.127	+1.530	.002	.002	3	4
HNSC	MED15P9 →	+0.406	+3.521	<.001	<.001	3	3
SKCM	B3GNT10 →	+0.747	+3.208	.003	.009	3	3
LUAD	MAGEA1 →	+1.869	+3.746	.001	.004	3	3
UCEC	COX5A →	+0.373	+2.513	<.001	<.001	3	3
UCEC	GEMIN4 →	+0.645	+2.807	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,960 associations by consensus.

Exploration

VEPH1 survival (RNA) · tumor vs normal (RNA) · all VEPH1 data types