VENTXP7

Across TCGA patient cohorts, VENTXP7 mutation is significantly associated with the RNA expression of many other genes, with 508 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VENTXP7-associated genes across cancer lineages are EEF1E1-BLOC1S5, TRAJ23, and PHF5A. Each is linked with VENTXP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both VENTXP7-to-partner and partner-to-VENTXP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EEF1E1-BLOC1S5 grouped by VENTXP7-low versus VENTXP7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VENTXP7→partner) and Y-score (partner→VENTXP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	EEF1E1-BLOC1S5 →	+0.055	+3.351	<.001	.008	3	2
UCEC	TRAJ23 →	+0.489	+2.256	.004	.006	3	2
UCEC	PHF5A →	+0.546	+3.378	.002	.004	3	1
UCEC	MTHFD1 →	+0.551	+3.387	.006	.004	3	1
UCEC	PRORP →	+0.400	+3.362	.002	.005	3	1
UCEC	GPR143 →	-0.814	-3.689	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 508 associations by consensus.

EEF1E1-BLOC1S5 by VENTXP7 expression — SKCM

Explore this box plot interactively →