VENTX

Across TCGA patient cohorts, VENTX mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible VENTX-associated genes across cancer lineages are CD8+ naive T-cells, Pericytes, and Mesangial cells. Each is linked with VENTX in more than 1 cancer types. Because this analysis shows association rather than direction, both VENTX-to-partner and partner-to-VENTX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by VENTX-low versus VENTX-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VENTX→partner) and Y-score (partner→VENTX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD8+ naive T-cells →	-0.035	-3.150	.029	.020	3	1
SKCM	Pericytes →	+0.096	+2.269	<.001	.021	3	1
UCEC	Mesangial cells →	-0.067	-2.936	.002	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ naive T-cells by VENTX expression — SKCM

Explore this box plot interactively →