VENTX

Across TCGA pan-cancer cohorts, VENTX RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of VENTX’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where VENTX RNA is more highly expressed in tumor relative to normal tissue. In most cancer types VENTX is over-expressed in tumor, although a few such as LUSC and UCEC show the opposite, repressed pattern.

COAD, KIRC, and THCA are the cancer types where VENTX tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VENTX RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.712	<.001	11	view →
KIRC	Male	IV	+0.639	<.001	11	view →
THCA	All	II,III,IV	+0.531	<.001	10	view →
LUSC	All	II,III,IV	−0.939	<.001	8	view →
UCEC	All	All	−0.833	<.001	6	view →
BRCA	Female	II,III,IV	−0.570	<.001	6	view →
BLCA	Male	IV	−0.537	.018	4	view →
LUAD	Male	II,III,IV	−0.423	.022	4	view →
KICH	All	All	−0.342	.015	4	view →
LIHC	All	All	+0.131	.011	3	view →
READ	All	All	+2.094	.006	2	view →
PRAD	All	All	−0.209	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

VENTX–COAD

Open the COAD breakdown →