VENTX

Across TCGA cell cohorts, VENTX RNA expression is significantly associated with the go_rna of many other GO terms, with 329 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VENTX-associated GO terms across cancer lineages are Purine ribonucleotide biosynthetic process, Negative regulation of endodermal cell differentiation, and Regulation of long-term synaptic depression. Each is linked with VENTX in more than 2 cancer types. Because this analysis shows association rather than direction, both VENTX-to-partner and partner-to-VENTX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleotide biosynthetic process grouped by VENTX-low versus VENTX-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VENTX→partner) and Y-score (partner→VENTX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Purine ribonucleotide biosynthetic process →	+0.042	+0.027	.008	.003	2	3
LUNG_SCLC	Negative regulation of endodermal cell differentiation →	+0.811	+0.038	.002	.007	2	3
BLOOD_Leukemia	Regulation of long-term synaptic depression →	-0.110	-0.727	<.001	.001	3	2
BLOOD_Leukemia	Negative regulation of lymphocyte chemotaxis →	+0.565	+0.654	.002	<.001	3	2
BLOOD_Leukemia	Positive regulation of bicellular tight junction assembly →	-0.138	-0.715	<.001	.001	3	2
BLOOD_Leukemia	Negative regulation of dopaminergic neuron differentiation →	-0.093	-0.685	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 329 associations by consensus.

Purine ribonucleotide biosynthetic process by VENTX expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →