VENTX

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, VENTX mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VENTX-associated genes across cancer lineages are DEFB129. Each is linked with VENTX in more than 1 cancer types. Because this analysis shows association rather than direction, both VENTX-to-partner and partner-to-VENTX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB129 grouped by VENTX-low versus VENTX-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VENTX→partner) and Y-score (partner→VENTX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaDEFB129 →+0.064+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DEFB129 by VENTX expression — BLOOD_Leukemia

Box plot of DEFB129 in VENTX-low vs VENTX-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration