VEGFA

Across TCGA patient cohorts, VEGFA RNA expression is significantly associated with the protein abundance of many other proteins, with 13,373 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible VEGFA-associated proteins across cancer lineages are FLT1, ANGPT2, and P4HA1. Each is linked with VEGFA in more than 8 cancer types. Because this analysis shows association rather than direction, both VEGFA-to-partner and partner-to-VEGFA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VEGFA versus FLT1 in CCRCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFA→partner) and Y-score (partner→VEGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FLT1 →	+0.682	+0.948	<.001	<.001	3	9
UCEC	ANGPT2 →	+0.744	+1.574	<.001	<.001	3	7
LUAD	P4HA1 →	+0.597	+1.083	<.001	<.001	3	7
GBM	PLOD2 →	+0.967	+1.870	<.001	<.001	3	7
OV	FN1 →	+1.102	+0.999	<.001	.002	3	6
BRCA	LOXL2 →	+0.852	+1.351	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,373 associations by consensus.

VEGFA vs FLT1 — CCRCC

Explore this scatter interactively →