VEGFA

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, VEGFA mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VEGFA-associated genes across cancer lineages are TTLL8. Each is linked with VEGFA in more than 1 cancer types. Because this analysis shows association rather than direction, both VEGFA-to-partner and partner-to-VEGFA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTLL8 grouped by VEGFA-low versus VEGFA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFA→partner) and Y-score (partner→VEGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETTLL8 →+0.006+6.022<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TTLL8 by VEGFA expression — LARGE_INTESTINE

Box plot of TTLL8 in VEGFA-low vs VEGFA-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration