Across TCGA patient cohorts, VDAC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,557 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VDAC1-associated proteins across cancer lineages are HSPA4, LARP1, and YTHDC2. Each is linked with VDAC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both VDAC1-to-partner and partner-to-VDAC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC1→partner) and Y-score (partner→VDAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HSPA4 →	+0.320	+0.688	<.001	<.001	3	7
LSCC	LARP1 →	+0.267	+0.452	<.001	<.001	3	7
OV	YTHDC2 →	+0.315	+0.599	<.001	<.001	3	7
GBM	CDKN1B →	-0.535	-0.343	<.001	<.001	3	6
PDAC	AK4 →	+0.597	+0.396	<.001	.002	3	6
OV	G3BP1 →	+0.250	+0.651	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,557 associations by consensus.

Exploration

VDAC1 survival (RNA) · tumor vs normal (RNA) · all VDAC1 data types