VCY

Across TCGA patient cohorts, VCY RNA expression is significantly associated with the go_rna of many other GO terms, with 907 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible VCY-associated GO terms across cancer lineages are Peroxisome organization, Mitotic cytokinesis, and Protein targeting to mitochondrion. Each is linked with VCY in more than 2 cancer types. Because this analysis shows association rather than direction, both VCY-to-partner and partner-to-VCY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peroxisome organization grouped by VCY-low versus VCY-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VCY→partner) and Y-score (partner→VCY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Peroxisome organization →	+0.080	+0.026	<.001	.005	3	3
STAD	Mitotic cytokinesis →	+0.075	+0.057	<.001	.002	3	2
STAD	Protein targeting to mitochondrion →	+0.071	+0.073	<.001	.004	3	2
ESCA	Phosphatidylcholine metabolic process →	+0.057	+0.035	.001	.002	3	2
LIHC	Regulation of binding →	+0.024	+0.008	<.001	<.001	3	2
SKCM	Regulation of DNA binding →	+0.026	+0.030	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 907 associations by consensus.

Peroxisome organization by VCY expression — ESCA

Explore this box plot interactively →