VCX3A

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, VCX3A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated VCX3A data layer compared with 17 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher VCX3A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated VCX3A expression acts as an unfavorable survival marker.

STAD and UCEC are the cancer types where VCX3A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianII,III,IV0.1130.711<.00124view →
UCECDFSMedianIII,IV0.1760.702.0046view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

VCX3A–STAD (OS)

Kaplan–Meier survival curve for VCX3A mutant vs wild-type samples in STAD.

Open the STAD breakdown →

Exploration