VCX

Across TCGA cell cohorts, VCX RNA expression is significantly associated with the go_rna of many other GO terms, with 565 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible VCX-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Positive regulation of telomere maintenance via telomere lengthening, and Sensory perception of light stimulus. Each is linked with VCX in more than 5 cancer types. Because this analysis shows association rather than direction, both VCX-to-partner and partner-to-VCX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribose phosphate biosynthetic process grouped by VCX-low versus VCX-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VCX→partner) and Y-score (partner→VCX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Ribose phosphate biosynthetic process →	+0.052	+1.031	<.001	.001	3	6
SKIN	Positive regulation of telomere maintenance via telomere lengthening →	+0.053	+0.969	<.001	.002	3	5
CNS	Sensory perception of light stimulus →	-0.053	-1.533	<.001	.003	3	5
CNS	Nucleic acid catabolic process →	+0.028	+1.114	.002	.007	3	4
CNS	Cytoplasmic translation →	+0.048	+1.365	.003	.005	3	4
SKIN	Spliceosomal snRNP assembly →	+0.061	+1.091	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 565 associations by consensus.

Ribose phosphate biosynthetic process by VCX expression — SKIN

Explore this box plot interactively →