VCPIP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VCPIP1 mutation is significantly associated with the RNA expression of many other genes, with 3,605 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VCPIP1-associated genes across cancer lineages are RNU7-10P, CD83P1, and RN7SKP286. Each is linked with VCPIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both VCPIP1-to-partner and partner-to-VCPIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-10P grouped by VCPIP1-low versus VCPIP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VCPIP1→partner) and Y-score (partner→VCPIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU7-10P →+0.628+2.857<.001.00433
SKCMCD83P1 →+0.073+2.592.001.00533
SKCMRN7SKP286 →+0.046+4.640<.001.00333
UCECPOLE2 →+0.483+2.091<.001<.00133
UCECLINC01809 →+0.081+1.899.002.00633
UCECMRPS18BP2 →+0.071+1.671.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,605 associations by consensus.

RNU7-10P by VCPIP1 expression — BLCA

Box plot of RNU7-10P in VCPIP1-low vs VCPIP1-high samples in BLCA.

Explore this box plot interactively →

Exploration