VCPIP1

Across TCGA cell cohorts, VCPIP1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VCPIP1-associated genes across cancer lineages are CCR8, FAM205C, and CCER1. Each is linked with VCPIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VCPIP1-to-partner and partner-to-VCPIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCR8 grouped by VCPIP1-low versus VCPIP1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VCPIP1→partner) and Y-score (partner→VCPIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	FAM205C →	+0.070	+4.930	<.001	.008	3	1
CNS	CCER1 →	+0.016	+5.754	<.001	.002	3	1
BREAST	CDH9 →	+0.030	+3.758	<.001	.007	3	1
BREAST	NKX2-4 →	+0.121	+3.672	<.001	.006	3	1
BREAST	TSPAN16 →	+0.035	+3.758	.009	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

CCR8 by VCPIP1 expression — SOFT_TISSUE

Explore this box plot interactively →