VCP

Across TCGA cell cohorts, VCP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,748 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VCP-associated GO terms across cancer lineages are tRNA export from nucleus, RNA export from nucleus, and Latent virus replication. Each is linked with VCP in more than 16 cancer types. Because this analysis shows association rather than direction, both VCP-to-partner and partner-to-VCP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA export from nucleus grouped by VCP-low versus VCP-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VCP→partner) and Y-score (partner→VCP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	tRNA export from nucleus →	+0.140	+0.996	.005	.003	3	17
OESOPHAGUS	RNA export from nucleus →	+0.128	+0.895	<.001	<.001	3	14
BREAST	Latent virus replication →	+0.163	+1.446	<.001	<.001	3	13
BREAST	Release from viral latency →	+0.163	+1.446	<.001	<.001	3	13
BONE	Positive regulation of mitotic cytokinesis →	+0.156	+0.474	.004	.002	3	13
CNS	Retrograde transport, endosome to Golgi →	+0.063	+0.800	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,748 associations by consensus.

tRNA export from nucleus by VCP expression — URINARY_TRACT

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