VCL

Across TCGA patient cohorts, VCL RNA expression is significantly associated with the protein abundance of many other proteins, with 15,558 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible VCL-associated proteins across cancer lineages are ACTN1, CNN2, and DAPK3. Each is linked with VCL in more than 7 cancer types. Because this analysis shows association rather than direction, both VCL-to-partner and partner-to-VCL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VCL versus ACTN1 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VCL→partner) and Y-score (partner→VCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACTN1 →	+0.757	+0.587	<.001	<.001	3	8
OV	CNN2 →	+0.840	+0.797	<.001	.001	3	8
UCEC	DAPK3 →	+0.622	+0.582	<.001	.001	3	8
UCEC	FILIP1L →	+1.041	+0.533	<.001	.002	3	8
UCEC	FLNA →	+0.660	+0.475	<.001	.001	3	8
UCEC	PDLIM7 →	+0.727	+0.459	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,558 associations by consensus.

VCL vs ACTN1 — UCEC

Explore this scatter interactively →