VAX1

Across TCGA cell cohorts, VAX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,230 significant associations in total. BONE shows the largest number of these associations.

The most reproducible VAX1-associated GO terms across cancer lineages are Positive regulation of synaptic transmission, Transcription initiation at RNA polymerase II promoter, and DNA-templated transcription initiation. Each is linked with VAX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both VAX1-to-partner and partner-to-VAX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of synaptic transmission grouped by VAX1-low versus VAX1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAX1→partner) and Y-score (partner→VAX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of synaptic transmission →	-0.080	-0.340	<.001	.006	3	7
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.075	+0.417	<.001	.001	3	7
OESOPHAGUS	DNA-templated transcription initiation →	+0.081	+1.108	<.001	.005	3	7
BLOOD_Leukemia	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.087	+0.004	<.001	.002	3	6
LUNG_NSCLC_LUSC	Sodium ion transmembrane transport →	-0.067	-0.331	.001	.001	3	6
OESOPHAGUS	Nuclear export →	+0.100	+1.088	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,230 associations by consensus.

Positive regulation of synaptic transmission by VAX1 expression — PANCREAS

Explore this box plot interactively →