VAV3-AS1

Across TCGA pan-cancer cohorts, VAV3-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated VAV3-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher VAV3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VAV3-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BRCA show a favorable association.

LGG, ESCA, and LUSC are the cancer types where VAV3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Tertile	All	0.625	0.859	<.001	51	view →
ESCA	OS	Median	III,IV	0.592	0.311	.003	30	view →
LUSC	OS	Quartile	II,III,IV	0.550	0.832	.025	20	view →
BRCA	DFS	Tertile	III,IV	0.926	0.812	.010	17	view →
CHOL	DFS	Tertile	III,IV	1.000	0.182	.034	12	view →
THYM	OS	Median	All	1.000	0.656	.005	9	view →
KICH	DFS	Tertile	All	0.657	0.887	.028	9	view →
READ	DFS	Tertile	III,IV	0.303	0.653	.043	9	view →
PCPG	OS	Tertile	All	0.340	0.975	.009	9	view →
BLCA	OS	Tertile	All	0.539	0.368	.040	8	view →
STAD	DFS	Median	IV	0.639	0.208	.019	7	view →
MESO	OS	Median	All	0.711	0.354	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

VAV3-AS1–LGG (OS)

Open the LGG breakdown →