VAV2

Across TCGA patient cohorts, VAV2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,204 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VAV2-associated proteins across cancer lineages are TRAF2, EHMT1, and BRD3. Each is linked with VAV2 in more than 5 cancer types. Because this analysis shows association rather than direction, both VAV2-to-partner and partner-to-VAV2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAV2 versus TRAF2 in LUAD, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VAV2→partner) and Y-score (partner→VAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRAF2 →	+0.314	+0.598	<.001	<.001	3	6
GBM	EHMT1 →	+0.405	+0.517	<.001	<.001	3	5
GBM	BRD3 →	+0.314	+0.452	.001	.004	2	5
GBM	FUBP3 →	+0.193	+0.490	<.001	<.001	3	4
GBM	GTF3C2 →	+0.284	+0.673	<.001	<.001	3	4
LUAD	GTF3C4 →	+0.237	+0.521	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,204 associations by consensus.

VAV2 vs TRAF2 — LUAD

Explore this scatter interactively →