VAV2

Across TCGA cell cohorts, VAV2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,438 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible VAV2-associated GO terms across cancer lineages are Response to oscillatory fluid shear stress, Cellular response to oscillatory fluid shear stress, and Vascular endothelial cell response to oscillatory fluid shear stress. Each is linked with VAV2 in more than 12 cancer types. Because this analysis shows association rather than direction, both VAV2-to-partner and partner-to-VAV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to oscillatory fluid shear stress grouped by VAV2-low versus VAV2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAV2→partner) and Y-score (partner→VAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to oscillatory fluid shear stress →	+0.134	+1.004	<.001	.004	3	13
BONE	Cellular response to oscillatory fluid shear stress →	+0.134	+1.004	<.001	.004	3	13
BONE	Vascular endothelial cell response to oscillatory fluid shear stress →	+0.134	+1.004	<.001	.004	3	13
LUNG_NSCLC_LUAD	Vascular endothelial growth factor receptor signaling pathway →	+0.137	+0.920	<.001	<.001	3	11
CNS	Nucleic acid transport →	+0.075	+0.948	<.001	<.001	3	10
CNS	RNA transport →	+0.075	+0.948	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,438 associations by consensus.

Response to oscillatory fluid shear stress by VAV2 expression — BONE

Explore this box plot interactively →