VAV2

Across TCGA cell cohorts, VAV2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,470 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible VAV2-associated genes across cancer lineages are PDXDC1, ALAD, and TMC4. Each is linked with VAV2 in more than 5 cancer types. Because this analysis shows association rather than direction, both VAV2-to-partner and partner-to-VAV2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAV2 versus PDXDC1 in LUNG_SCLC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAV2→partner) and Y-score (partner→VAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PDXDC1 →	-0.656	-0.726	.006	.004	3	6
LUNG_NSCLC_LUAD	ALAD →	-0.718	-0.590	.002	.003	3	6
BREAST	TMC4 →	-2.278	-0.746	<.001	.003	3	5
LIVER	EIF2AK3 →	-0.990	-0.779	.003	<.001	3	5
LUNG_SCLC	CCDC149 →	-1.414	-1.012	<.001	<.001	3	5
LUNG_SCLC	RNF19A →	-1.332	-0.941	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,470 associations by consensus.

VAV2 vs PDXDC1 — LUNG_SCLC

Explore this scatter interactively →