VASP

Across TCGA patient cohorts, VASP protein abundance is significantly associated with the protein abundance of many other proteins, with 29,186 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VASP-associated proteins across cancer lineages are ARPC5, CAP1, and CORO1A. Each is linked with VASP in more than 8 cancer types. Because this analysis shows association rather than direction, both VASP-to-partner and partner-to-VASP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VASP versus ARPC5 in GBM, with a Pearson correlation of 0.78.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VASP→partner) and Y-score (partner→VASP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARPC5 →	+0.404	+0.552	<.001	<.001	3	9
LSCC	CAP1 →	+0.356	+0.399	<.001	<.001	3	9
LSCC	CORO1A →	+0.608	+0.361	<.001	<.001	3	8
GBM	STK10 →	+0.516	+0.576	<.001	<.001	3	8
GBM	HK3 →	+1.274	+0.635	<.001	<.001	3	8
GBM	MYO1F →	+0.738	+0.508	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 29,186 associations by consensus.

VASP vs ARPC5 — GBM

Explore this scatter interactively →