VASN

Across TCGA cell cohorts, VASN mutation is significantly associated with the RNA expression of many other genes, with 366 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VASN-associated genes across cancer lineages are OR1J2, CCR8, and FAM205C. Each is linked with VASN in more than 1 cancer types. Because this analysis shows association rather than direction, both VASN-to-partner and partner-to-VASN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1J2 grouped by VASN-low versus VASN-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VASN→partner) and Y-score (partner→VASN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR1J2 →	+0.055	+2.991	.003	.007	3	2
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	FAM205C →	+0.063	+4.930	<.001	.008	3	1
BLOOD_Lymphoma	CIB4 →	+0.346	+5.209	<.001	.005	3	1
BLOOD_Leukemia	GHRHR →	+0.291	+3.536	<.001	.001	3	1
BLOOD_Leukemia	CPXCR1 →	+0.082	+2.971	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 366 associations by consensus.

OR1J2 by VASN expression — BLOOD_Leukemia

Explore this box plot interactively →