VASH2

Across TCGA patient cohorts, VASH2 mutation is significantly associated with the RNA expression of many other genes, with 1,713 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VASH2-associated genes across cancer lineages are MIR3135A, SNORD82, and SNORD116-16. Each is linked with VASH2 in more than 2 cancer types. Because this analysis shows association rather than direction, both VASH2-to-partner and partner-to-VASH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3135A grouped by VASH2-low versus VASH2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VASH2→partner) and Y-score (partner→VASH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR3135A →	+1.424	+5.602	<.001	.004	3	3
UCEC	SNORD82 →	+0.453	+1.817	<.001	.004	3	2
UCEC	SNORD116-16 →	+0.309	+1.966	.003	.002	3	2
UCEC	TRAJ11 →	+0.468	+2.176	<.001	<.001	3	2
LUAD	PMCHL1 →	+0.066	+5.279	<.001	.006	3	2
LUAD	MIR3661 →	+0.474	+5.157	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,713 associations by consensus.

MIR3135A by VASH2 expression — COAD

Explore this box plot interactively →