VASH1

Across TCGA patient cohorts, VASH1 mutation is significantly associated with the RNA expression of many other genes, with 457 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VASH1-associated genes across cancer lineages are TSPY4, VAV3-AS1, and LINC00997. Each is linked with VASH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VASH1-to-partner and partner-to-VASH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY4 grouped by VASH1-low versus VASH1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VASH1→partner) and Y-score (partner→VASH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TSPY4 →	+0.069	+7.930	<.001	.008	3	2
UCEC	VAV3-AS1 →	+0.137	+2.036	.009	.003	3	2
UCEC	LINC00997 →	-0.474	-3.576	.001	.002	3	1
UCEC	SEPTIN14P19 →	+0.027	+4.022	<.001	<.001	3	1
UCEC	AK4P1 →	+0.516	+2.561	.001	.009	3	1
UCEC	MIR3189 →	+1.211	+2.906	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 457 associations by consensus.

TSPY4 by VASH1 expression — LUAD

Explore this box plot interactively →