VAMP7

Across TCGA patient cohorts, VAMP7 mutation is significantly associated with the RNA expression of many other genes, with 3,478 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VAMP7-associated genes across cancer lineages are BCAS2P3, RNA5SP415, and YTHDF3-AS1. Each is linked with VAMP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both VAMP7-to-partner and partner-to-VAMP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCAS2P3 grouped by VAMP7-low versus VAMP7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP7→partner) and Y-score (partner→VAMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	BCAS2P3 →	+0.057	+4.625	.002	.008	3	2
UCEC	RNA5SP415 →	+0.352	+1.903	.002	.004	3	2
UCEC	YTHDF3-AS1 →	+0.644	+2.024	<.001	.005	3	1
UCEC	CHCHD2P3 →	+0.091	+1.755	.006	.002	3	1
UCEC	LINC01050 →	+0.203	+1.999	<.001	<.001	3	1
UCEC	CCL5 →	+0.944	+3.186	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,478 associations by consensus.

BCAS2P3 by VAMP7 expression — LUSC

Explore this box plot interactively →