VAMP7

Across TCGA cell cohorts, VAMP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,892 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible VAMP7-associated GO terms across cancer lineages are Negative regulation of organelle assembly, Nuclear membrane organization, and Macroautophagy. Each is linked with VAMP7 in more than 11 cancer types. Because this analysis shows association rather than direction, both VAMP7-to-partner and partner-to-VAMP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of organelle assembly grouped by VAMP7-low versus VAMP7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP7→partner) and Y-score (partner→VAMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.096	+0.998	.001	.001	3	12
BLOOD_Lymphoma	Nuclear membrane organization →	+0.087	+1.046	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Macroautophagy →	+0.065	+0.992	.001	.003	3	11
KIDNEY	Natural killer cell degranulation →	+0.292	+0.936	.004	.002	3	11
LUNG_NSCLC_LUSC	Regulation of angiotensin-activated signaling pathway →	+0.135	+0.871	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Phospholipid dephosphorylation →	+0.063	+0.893	.003	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,892 associations by consensus.

Negative regulation of organelle assembly by VAMP7 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →