Across TCGA patient cohorts, VAMP2 RNA expression is significantly associated with the RNA expression of many other genes, with 18,619 significant associations in total. ACC shows the largest number of these associations.

The most reproducible VAMP2-associated genes across cancer lineages are HDAC5, NICN1, and ZBTB4. Each is linked with VAMP2 in more than 32 cancer types. Because this analysis shows association rather than direction, both VAMP2-to-partner and partner-to-VAMP2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP2→partner) and Y-score (partner→VAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	HDAC5 →	+1.066	+1.160	<.001	<.001	3	33
UCS	NICN1 →	+1.128	+1.190	<.001	<.001	3	33
UCS	ZBTB4 →	+1.122	+1.039	<.001	<.001	3	33
ACC	FXR2 →	+0.884	+1.027	<.001	<.001	3	32
PAAD	APBB1 →	+1.065	+0.856	<.001	<.001	3	32
UCS	CTC1 →	+1.133	+1.143	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,619 associations by consensus.

Exploration

VAMP2 survival (RNA) · tumor vs normal (RNA) · all VAMP2 data types