Across TCGA cell cohorts, VAMP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,467 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VAMP2-associated GO terms across cancer lineages are Eosinophil activation, Eosinophil degranulation, and Eosinophil activation involved in immune response. Each is linked with VAMP2 in more than 18 cancer types. Because this analysis shows association rather than direction, both VAMP2-to-partner and partner-to-VAMP2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP2→partner) and Y-score (partner→VAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Eosinophil activation →	+0.229	+1.412	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Eosinophil degranulation →	+0.229	+1.412	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Eosinophil activation involved in immune response →	+0.229	+1.412	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.063	+0.752	.002	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.080	+0.999	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of translation at synapse, modulating synaptic transmission →	+0.116	+0.889	.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,467 associations by consensus.

Exploration

VAMP2 survival (RNA) · tumor vs normal (RNA) · all VAMP2 data types