Across TCGA cell cohorts, VAMP2 protein abundance is significantly associated with the RNA expression of many other genes, with 984 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible VAMP2-associated genes across cancer lineages are CUL4A, DKK1, and MTO1. Each is linked with VAMP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both VAMP2-to-partner and partner-to-VAMP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP2→partner) and Y-score (partner→VAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CUL4A →	+0.773	+1.454	.004	.004	3	4
OVARY	DKK1 →	+5.956	+1.403	<.001	.001	3	3
OVARY	MTO1 →	+0.781	+1.390	.007	.002	3	3
OVARY	ARF4 →	+1.033	+1.390	.008	.002	3	3
OVARY	C3orf80 →	+0.385	+1.589	.001	.005	3	3
OVARY	CD82 →	-2.360	-1.310	.004	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 984 associations by consensus.

Exploration

VAMP2 survival (RNA) · tumor vs normal (RNA) · all VAMP2 data types