Across TCGA cell cohorts, VAMP2 protein abundance is significantly associated with the go_rna of many other GO terms, with 643 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible VAMP2-associated GO terms across cancer lineages are Regulation of mitotic sister chromatid separation, Regulation of mitotic spindle checkpoint, and Regulation of sister chromatid segregation. Each is linked with VAMP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both VAMP2-to-partner and partner-to-VAMP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP2→partner) and Y-score (partner→VAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of mitotic sister chromatid separation →	+0.141	+1.403	<.001	.001	3	3
OVARY	Regulation of mitotic spindle checkpoint →	+0.124	+1.403	.003	.001	3	3
OVARY	Regulation of sister chromatid segregation →	+0.126	+1.867	.001	.001	3	3
OVARY	Regulation of chromosome segregation →	+0.120	+1.386	.002	.002	3	3
OVARY	Regulation of spindle checkpoint →	+0.180	+2.123	.001	.007	3	3
OVARY	Regulation of mitotic cell cycle spindle assembly checkpoint →	+0.124	+1.403	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 643 associations by consensus.

Exploration

VAMP2 survival (RNA) · tumor vs normal (RNA) · all VAMP2 data types