UXT-AS1

Across TCGA pan-cancer cohorts, UXT-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated UXT-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher UXT-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated UXT-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and OV show a favorable association.

ACC, OV, and KICH are the cancer types where UXT-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	III,IV	0.672	0.080	<.001	68	view →
OV	OS	Median	All	0.738	0.645	.003	52	view →
KICH	DFS	Quartile	III,IV	0.189	1.000	.002	51	view →
ESCA	DFS	Median	All	0.378	0.615	<.001	40	view →
LGG	DFS	Tertile	All	0.640	0.812	<.001	37	view →
LUSC	OS	Quartile	All	0.826	0.678	.005	29	view →
THCA	OS	Median	III,IV	0.332	1.000	.010	25	view →
SKCM	DFS	Tertile	All	0.661	0.553	.009	22	view →
KIRC	DFS	Tertile	All	0.857	0.724	.005	20	view →
UVM	OS	Tertile	III,IV	0.378	0.867	.014	16	view →
KIRP	DFS	Median	All	0.360	0.727	<.001	13	view →
LAML	DFS	Tertile	All	0.215	0.526	.019	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

UXT-AS1–ACC (DFS)

Open the ACC breakdown →