Across TCGA patient cohorts, UVRAG mutation is significantly associated with the RNA expression of many other genes, with 4,071 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UVRAG-associated genes across cancer lineages are NOL12, H2AC14, and MTND6P16. Each is linked with UVRAG in more than 1 cancer types. Because this analysis shows association rather than direction, both UVRAG-to-partner and partner-to-UVRAG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UVRAG→partner) and Y-score (partner→UVRAG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOL12 →	+0.267	+2.254	.004	.005	3	2
UCEC	H2AC14 →	+0.876	+2.595	<.001	<.001	3	2
CESC	MTND6P16 →	+0.054	+5.252	<.001	.002	3	2
CESC	RNA5SP303 →	+0.169	+4.384	.001	.008	3	2
CESC	NDUFB9P1 →	+0.210	+4.200	<.001	.004	3	2
SKCM	RPS7P13 →	+0.090	+4.359	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,071 associations by consensus.

Exploration

UVRAG survival (RNA) · tumor vs normal (RNA) · all UVRAG data types