Across TCGA cell cohorts, UVRAG mutation is significantly associated with the RNA expression of many other genes, with 87 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UVRAG-associated genes across cancer lineages are MTRNR2L6, SLCO1C1, and MYL3. Each is linked with UVRAG in more than 1 cancer types. Because this analysis shows association rather than direction, both UVRAG-to-partner and partner-to-UVRAG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UVRAG→partner) and Y-score (partner→UVRAG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	MTRNR2L6 →	+0.130	+4.357	<.001	.006	3	1
BREAST	SLCO1C1 →	+0.142	+2.614	<.001	.009	3	1
BREAST	MYL3 →	+0.544	+2.866	<.001	.008	3	1
BREAST	ZNF80 →	+0.057	+3.361	<.001	.001	3	1
BREAST	CLDN24 →	+0.123	+2.830	<.001	.009	3	1
BREAST	H4C6 →	+0.179	+2.969	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

Exploration

UVRAG survival (RNA) · tumor vs normal (RNA) · all UVRAG data types