UTP6

Across TCGA cell cohorts, UTP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,954 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UTP6-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Maturation of SSU-rRNA, and Centriole replication. Each is linked with UTP6 in more than 14 cancer types. Because this analysis shows association rather than direction, both UTP6-to-partner and partner-to-UTP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by UTP6-low versus UTP6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP6→partner) and Y-score (partner→UTP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of rRNA processing →	+0.127	+0.695	<.001	<.001	3	15
BLOOD_Myeloma	Maturation of SSU-rRNA →	+0.128	+0.766	<.001	<.001	3	14
LUNG_SCLC	Centriole replication →	+0.079	+0.576	.009	.004	2	14
BLOOD_Myeloma	Resolution of DNA recombination intermediates →	+0.132	+0.556	<.001	.001	3	13
PANCREAS	DNA recombination →	+0.061	+0.562	<.001	<.001	3	13
PANCREAS	Double-strand break repair →	+0.056	+0.512	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,954 associations by consensus.

Positive regulation of rRNA processing by UTP6 expression — BLOOD_Lymphoma

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