UTP6

Across TCGA pan-cancer cohorts, UTP6 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated UTP6 data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher UTP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UTP6 expression acts as an unfavorable survival marker, although some lineages such as READ and THYM show a favorable association.

KIRP, MESO, and LIHC are the cancer types where UTP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	III,IV	0.129	0.680	<.001	115	view →
MESO	OS	Median	All	0.404	0.673	<.001	114	view →
LIHC	OS	Median	All	0.707	0.840	<.001	102	view →
ACC	DFS	Median	All	0.198	0.667	<.001	98	view →
KIRC	DFS	Median	IV	0.184	0.504	<.001	63	view →
HNSC	OS	Quartile	III,IV	0.672	0.815	.003	54	view →
LGG	DFS	Median	All	0.639	0.831	<.001	52	view →
READ	OS	Tertile	All	0.853	0.322	.004	51	view →
BLCA	DFS	Median	All	0.484	0.693	.004	46	view →
UVM	DFS	Quartile	III,IV	0.170	0.813	.003	17	view →
LUAD	OS	Tertile	All	0.235	0.559	.003	17	view →
THYM	OS	Median	All	1.000	0.706	<.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

UTP6–KIRP (OS)

Open the KIRP breakdown →