UTP3

Across TCGA pan-cancer cohorts, UTP3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UTP3 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UTP3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UTP3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where UTP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.616	0.872	<.001	83	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.432	.010	26	view →
LSCC	DFS	Median	II,III,IV	0.853	0.545	.011	11	view →
PDAC	OS	Median	IV	0.395	0.937	.026	3	view →
HNSC	DFS	Tertile	III,IV	0.936	1.000	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UTP3–CCRCC (DFS)

Open the CCRCC breakdown →